A Prospective Study of Impedance Platelet Count and Mean Platelet Volume in Case of Severe Microcytosis

Abstract

Introduction: Microcytosis is a condition in which red blood cells are measured by their mean corpuscular volume 2. Microcytosis is characteristics of Iron deficiency anemia.1 Both Thrombocytosis and thrombocytopenia may be seen in severe microcytosis although thrombocytosis is more commonly seen.
Aim and Objectives: To study the values of impedance platelet count and mean platelet volume in case of severe microcytosis.
Materials and Method: A prospective study of 150 cases was carried out from 1st July 2019 to 31st October 2019 in Department of Pathology, B.J. Medical college, Ahmedabad. Study of platelet count and mean platelet volume of 150 cases with low mean corpuscular volume (MCV) was done.
Results: A total 150 cases with severe microcytosis (MCV < 60 fl) were evaluated for platelet count and mean platelet volume. Thrombocytosis was seen in 85 cases(56.7%), thrombocytopenia in 15 cases(10%), whereas normal platelet count was seen in 50 cases(33.3%). The mean platelet volume was low in 75 cases(50%) , high in 10 cases(6.7%), normal in 65 cases(43.3).
Conclusion: In severe microcytosis, both thrombocytosis and thrombocytopenia may occur although the incidence of thrombocytosis was high in our study. There is an inverse relationship of mean platelet volume and platelet count in case of severe microcytosis.