Integration of a Comprehensive Ultrasound Assessment in the Prognostic Modeling of benign and Malignant Ovarian Tumors

Authors

  • Tairova Madina Ilkhom Qizi 1Assistant at the Department of Radiology, Tashkent Medical Academy
  • Xayitboyeva Mukhayyo Ravshanovna Assistant at the Department of Radiology, Tashkent Medical Academy
  • Kalash Dwivedi Fourth Year Medical Student at the Tashkent Medical Academy Tashkent Uzbekistan

DOI:

https://doi.org/10.37506/23srgk96

Abstract

Ovarian tumors can be challenging to diagnose and treat, especially in areas with limited access to advanced medical care. During routine prenatal ultrasounds, abnormal growths in the ovaries can be unexpectedly discovered. In clinical practice, it is essential to accurately differentiate between benign and malignant ovarian tumors in order  to develop appropriate treatment plans. Ultrasound imaging has become the preferred diagnostic tool. The aim of  this article is to examine the ultrasound characteristics of ovarian and adnexal growths and to explore how these  characteristics, along with other clinical factors, can aid in predicting the likelihood of ovarian cancer.

References

GLOBOCAN. Ovarian cancer incidence in Uzbekistan. International Agency for Research on Cancer. 2020 [cited 2024 Jun 19]. Available from:

https://gco.iarc.fr/today/data/factsheets/populations/860-uzbekistan-fact-sheets.pdf

International Agency for Research on Cancer. Cervical cancer burden in Uzbekistan.2018 [cited 2024 Jun 19]. Available from: https://www.iarc.fr/news-events/iarc-reports/

American Cancer Society. Ovarian Cancer Survival Rates by Stage. 2020 [cited 2024 Jun 19]. Available from: https://www.cancer.org/cancer/ovarian-cancer/detection-diagnosis-staging/survival-rates.html

Jacobs I, Bast RC. The CA 125 tumor-associated antigen: a review of the literature. Hum Reprod. 1989;4(1):1-12.

Gentry-Maharaj A, Burnell M, Sharma A, et al. Serum CA125 in the differential diagnosis of malignant and benign pelvic masses: a prospective study of 629 women. Br J Cancer. 2010;103:882–888.

Timmerman D, Testa AC, Bourne T, et al. Simple ultrasound rules to distinguish between benign and malignant adnexal masses before surgery: prospective validation by IOTA group. BMJ. 2008;336:1481.

Khodjibekov MK, Ismailova MK. Differential diagnosis of ovarian tumors. J Clin Exp Oncol. 2021;1(15).

Ismailova MX, Nigmatjonov AS, Usmanova ZI. Role of Ultrasound Imaging in the Differential Diagnosis of Benign and Malignant Ovarian Cancer. Int J Psychosoc Rehabil. 2020;24(08):4926-4930.

Lee SJ, Oh HR, Na S, Hwang HS, Lee SM. Ultrasonographic ovarian mass scoring system for predicting malignancy in pregnant women with ovarian mass. Obstet Gynecol Sci. 2022;65(1):1-13.

Sadow CA, Park KJ. Early detection and screening for ovarian cancer. Radiol Clin North Am. 2018;56(4):595-606.

Sassone AM, Timor-Tritsch IE, Artner A, Withoff C, Warner WB. Transvaginal sonographic characterization of ovarian disease: evaluation of a new score system to predict ovarian malignancy. Obstet Gynecol. 1991;78(1):70-76.

Diagnosis and treatment of benign ovarian neoplasms from the perspective of cancer prevention (clinical recommendations treatment protocol) edited by Adamyan LV. Moscow: 2018.

Ismailova MH, Khayitboeva MR, Tairova MI. MRI and ultrasound in the diagnosis of ovarian formations. Int Sci Pract J "Eurasian J Oncol". 2022;10(2): appendix (online). XIII Congress of Oncologists and Radiologists of the CIS and Eurasia. April 27-29, 2022, Kazakhstan, 263.

Timmerman D, Testa AC, Bourne T, et al. Simple ultrasound rules to distinguish between benign and malignant adnexal masses before surgery: prospective validation by IOTA group. BMJ. 2008;336:1481.

Memarzadeh S, Berek JS. Advances in the management of epithelial ovarian cancer. J Clin Oncol. 2015;33:3075-3083.

Talaat A, Helmy MA, Saadawy SF. Evaluation of miRNA-21 and CA-125 as a promising diagnostic biomarker in patients with ovarian cancer. Egypt J Med Hum Genet. 2022;23:123. Available from: https://doi.org/10.1186/s43042-022-00342-5

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Published

2024-06-25

How to Cite

Integration of a Comprehensive Ultrasound Assessment in the Prognostic Modeling of benign and Malignant Ovarian Tumors. (2024). International Journal of Contemporary Pathology, 10(2). https://doi.org/10.37506/23srgk96