Extranasopharyngeal Angiofibroma of Maxillary Sinus: A Diagnostic Dilemma
DOI:
https://doi.org/10.37506/tawkkj25Keywords:
Nasopharyngeal angiofibroma, antrochoanal polyp, sphenopalatine foramen, pterygoid, rhinorrhoea, epistaxis.Abstract
Nasopharyngeal angiofibroma is a benign neoplasm of the nasopharynx with a propensity for aggressive local spread. It is responsible for 0.5% of head and neck cancer cases. Primarily affected are teenagers and young adults in the age
range of 14–25 years. It is an aggressive tumor that frequently spreads locally, destructive, including the base of the skull and the cranium. Evidence points to an androgen-dependent tumor given the substantial preference for young guys. Usually, the tumor originates around the sphenopalatine foramen. We present a case of angiofibroma in a young adult arising from the lateral wall of the nasal cavity around the maxillary sinus, masquerading as an antrochoanal polyp. Diagnostic nasal endoscopy was suggestive of an antrochoanal polyp. NCCT nose and PNS showed that the tumor originated from the lateral wall of the nasal cavity around maxillary sinus ostium with and left maxillary sinus opacification. Histopathological examination shows dense fibrocollagenous stromal proliferation interspersed with staghorns of various sizes and numerous thin-walled vessels, characteristic features of juvenile nasopharyngeal angiofibroma. After surgical resection, the person was followed for up to six months without tumor recurrence.
Downloads
References
Coutinho-Camillo CM, Brentani MM, Nagai MA.
Genetic alterations in juvenile nasopharyngeal
angiofibromas. Head & Neck: Journal for the Sciences
and Specialties of the Head and Neck. 2008;30(3):
-400.
Liu Z-f, Wang D-h, Sun X-c, Wang J-j, Hu L, Li H,
et al. The site of origin and expansive routes of juvenile
nasopharyngeal angiofibroma (JNA). International
journal of pediatric otorhinolaryngology. 2011;75(9):
-92.
WH Dane-Annals of Otology,Rhinology &
Laryngology,1954-journals.sagepub.com.
Abraham SC, Montgomery EA, Giardiello FM,
Wu T-T. Frequent β-catenin mutations in juvenile
nasopharyngeal angiofibromas. The American journal
of pathology. 2001;158(3):1073-8.
Zhang PJ, Weber R, Liang H-H, Pasha TL, LiVolsi
VA. Growth factors and receptors in juvenile
nasopharyngeal angiofibroma and nasal polyps: an
immunohistochemical study. Archives of pathology
& laboratory medicine. 2003;127(11):1480-4.
Huang RY, Damrose EJ, Blackwell KE, Cohen AN,
Calcaterra TC. Extranasopharyngeal angiofibroma.
International journal of pediatric otorhinolaryngology.
;56(1):59-64.
Windfuhr J, Remmert S. Extranasopharyngeal
angiofibroma: etiology, incidence and management.
Acta oto-laryngologica. 2004;124(8):880-9.
Handa K, Kumar A, Singh M, Chhabra AH.
Extranasopharyngeal angiofibroma arising from
the nasal septum. International journal of pediatric
otorhinolaryngology. 2001;58(2):163-6.
Szymańska A, Szymański M, Morshed K,
Czekajska-Chehab E, Szczerbo-Trojanowska M.
Extranasopharyngeal angiofibroma: clinical and
radiological presentation. European Archives of Oto-
Rhino-Laryngology. 2013;270(2):655-60.
Saylam G, Yücel OT, Sungur A, Önerci M. Proliferation,
angiogenesis and hormonal markers in juvenile
nasopharyngeal angiofibroma. International journal
of pediatric otorhinolaryngology. 2006;70(2):227-34.
Downloads
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.