Microbes and Immunity: The Periodontal Battle Zone

Abstract

Periodontal disease is known around the world as a significant health concern and a common cause of
adult tooth loss. Periodontal diseases are common inflamed disorders such as gingivitis and periodontitis
caused by the pathogens present in the biofilm which is seen subgingivally such as Aggregatibacter
actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola and Tannerella forsythia that
activate inflammatory, innate and adaptive responses of the immune system. The immune system plays a
vital role in preservation from pathogens with the maintenance of commensal microbiota at the mucosal
surface. This article is focused on discussing the role of microbes and the basis and concept of immunology
in periodontal disease in brief