Chronic Myeloid Leukemia and Associated Oral Manifestations

Abstract

Background: Leukemia defined as a hematological disorder associated with proliferating white blood cellforming tissues as resultant increasing of circulating immature white blood cells or abnormal cells.
Aims of the study: To investigate clinically the oral manifestations or discomfort oral features in patients
with chronic myeloid leukemia.
Subjects, Materials and Methods: Thirty- three patients participated (17 males and 16 females) in the
current study with chronic myeloid leukemia already.
Results: Total numbers of cases were (33). (17 males and 16 females), the percentages of these results
showed gingival bleeding (87%), fungal infection (84%), oral petechiae (72%), gingival overgrow (63%),
and then finally painless oral ulceration (60%), The early diagnosis of this disease knowing that the first
clinical symptoms of leukemia happen in the oral cavity with normal or show challenging changes in initial
laboratory tests.
Conclusions: Because of their clinical importance for early diagnosis, all such lesions or pathological status
deserves the full attention of the doctors (like oral physician and general physician).