Synthesis, Characterization of New Tris Hydrazones based on Cyanuric Acid and Studies the Biological Activity as Antibacterial and Antifunga

Authors

  • Thaer Saleh Ghali

DOI:

https://doi.org/10.37506/ijfmt.v14i1.142

Keywords:

Cyanuric acid , Hydrazones , antibacterial, 1,3,5-Triazinane-2,4,6-trione, antifungal

Abstract

In this study synthesis of new Tris Hydrazones derived from Cyanuric acid , these compounds synthesized by reaction of Cyanuric acid with Chloro ethyl acetate to product [I], then converted it to acid Hydrazide [II] by reacted with Hydrazine hydrate(80%) in absolute ethanol as a solvent. Compound [II] refluxed with different aromatic aldehyde in present of Glacial acetic acid (GAA) as a catalyst to formation new Tris Hydrazones [III]a-f. All new compounds were synthesized characterization by FT-IR and 1H-13CNMR spectroscopy. The biological activity of new Tris Hydrazones studies against to positive and negative Gram bacteria also test it against to Candida albicans as a sample of Fungi.

Author Biography

  • Thaer Saleh Ghali

    Directorate of Education Dhi Qar, Ministry of Education, Iraq

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Published

2020-01-16

How to Cite

Synthesis, Characterization of New Tris Hydrazones based on Cyanuric Acid and Studies the Biological Activity as Antibacterial and Antifunga. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(1), 753-758. https://doi.org/10.37506/ijfmt.v14i1.142