Synthesis, Characterization of New Tris Hydrazones based on Cyanuric Acid and Studies the Biological Activity as Antibacterial and Antifunga
DOI:
https://doi.org/10.37506/ijfmt.v14i1.142Keywords:
Cyanuric acid , Hydrazones , antibacterial, 1,3,5-Triazinane-2,4,6-trione, antifungalAbstract
In this study synthesis of new Tris Hydrazones derived from Cyanuric acid , these compounds synthesized by reaction of Cyanuric acid with Chloro ethyl acetate to product [I], then converted it to acid Hydrazide [II] by reacted with Hydrazine hydrate(80%) in absolute ethanol as a solvent. Compound [II] refluxed with different aromatic aldehyde in present of Glacial acetic acid (GAA) as a catalyst to formation new Tris Hydrazones [III]a-f. All new compounds were synthesized characterization by FT-IR and 1H-13CNMR spectroscopy. The biological activity of new Tris Hydrazones studies against to positive and negative Gram bacteria also test it against to Candida albicans as a sample of Fungi.
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Published
2020-01-16
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https://creativecommons.org/licenses/by-nc/2.0/deed.en
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Synthesis, Characterization of New Tris Hydrazones based on Cyanuric Acid and Studies the Biological Activity as Antibacterial and Antifunga. (2020). Indian Journal of Forensic Medicine & Toxicology, 14(1), 753-758. https://doi.org/10.37506/ijfmt.v14i1.142