Assessment of Hyperurcemia in Patient with End Stage Chronic Kidney Disease

Abstract

Chronic kidney disease (CKD) has become a global public health problem because of its high prevalence and the accompanying increase in the risk of end-stage renal disease, cardiovascular disease, and premature death. Progression of CKD is associated with a number of serious complications including increased incidence of cardiovascular disease, hyperlipidemia, anemia and metabolic bone disease. Hyperurcemia may be a major contributor to the development of progression of chronic kidney disease (CKD). Although there is no clear cutoff uric acid (UA) value associated to the risk for kidney damage, it appears to be an increased risk as UA rises.