Effect of Non-Computerized Cognitive Remediation and Risperidone to Improve Disability Function in Schizophrenia

Abstract

The aim of the study was to find out the effect of non-computerized cognitive remediation and risperidone
therapy to improve cognitive function and disability condition in schizophrenia patients. This study was an
experimental research design, with fourteen participants divided into two group as the experimental group
and the control group. The experimental and control groups both received Risperidone. In addition, the
experimental group was given the non-computerized cognitive remediation (CR). The non-computerized
cognitive remediation will be carried out in 12 sessions (3 sessions per week) using mainly paper and
pencil tasks and is based on cognitive strategy instruction. Moreover, all samples will be measured for
PANSS (Positive and Negative Symptom Scale), WHODAS 2.0 (World Health Organization Disability
Assessment Schedule), and SCoRS Vi (Schizophrenia Cognition Rating Scales Indonesian Version) scores.
As the results, both experimental and control group showed a significant decrease in the SCoRS Vi and
WHODAS 2.0 score (p=0.001). However, the experimental group showed greater improvement compared
to the control group. Synergistic effect of Non-computerized Cognitive Remediation and Risperidone can
improve disability condition in schizophrenia patients.