Study the Relation of Copeptin and Some Biochemical Parameters in with Obesity in Kirkuk City

Abstract

In this Case-Control Study, One hundred thirty six adult subjects with obesity were separated to take part
in the current research. At the Kirkuk General Hospital in Kirkuk City- Iraq, Applying this study had done
for the duration of the 16th of February to the end of June 2020 Adult subjects with obesity outpatient
attended to Kirkuk General Hospital were enrolled in this research. Ages of adult persons were amid 18 to
62 years and they were from the center and periphery of Kirkuk City. Thirty one adult persons with obesity
were considered as a study group, thirty adult persons were measured as control, sixty-three adult persons
didn’t assembly the inclusion criteria and 20 adult persons refuse to participate in this study because of the
in agreement of their people. Blood sample were collected from each adult person for determination of
copepetin, lipid profile and blood sugar determination. The study revealed that the mean of copeptin was
higher in obese group as compared with healthy control group (166.4±81.8 vs. 35.01±12.3 pg/ml). The
study showed a significant difference between obese and the control group regarding fasting blood sugar
(FBS) (119.3±12.5 and 98.2±11.6 mg/dl) respectively. The study showed that, the mean serum triglyceride
was recorded to be higher in obese group (110.4±45.3 mg/dl) as compared with healthy control group (90.9
±29.1 mg/dl). The study showed that, the mean of serum cholesterol was higher in obese group (170.7±36.3
mg/dl) as compared with healthy control group (151.7 ±29.6 mg/dl). The study showed that, the lowest
mean of serum HDL was recorded in obese group (41.6±14.5 mg/dl) as compared with healthy control group
(61.44 ±7.63 mg/dl). The study showed that, the highest mean of serum LDL and VLDL was recorded in
obese group as compared with healthy control group. The study showed negative correlation between serum
copeptin and FBS in obese individuals. It was concluded that, Serum copeptin was significantly higher in
obese group as compared with healthy control group and there was a negative correlation between copeptin
and blood sugar levels