Effect of Cigarette Smoking on Vitamin C in Non Pregnant and Pregnant Women

Abstract

Introduction: It is perceived that smoking cigarettes during pregnancy is unfortunate and can prompt
expanded unconstrained early abortion in the first trimester, premature abruption of the placenta, preterm
delivery, decreased birth weight and SIDS. All things considered, children destined to mothers who smoke
during pregnancy weigh 150-300 gram not exactly those destined to mothers who don’t smoke and the
danger of little for-gestational age among ladies who smoke is at any rate twice as high as among ladies
who don’t smoke. For more seasoned ladies, the effect of smoking during pregnancy on fetal development
and preterm conveyance are more noteworthy. The danger of placental issues can be expanded by long haul
smoking.
Aim: Effect of cigarette smoking in non-pregnant and pregnant women’s on the blood serum level of vitamin
C
Material and Methods: The present study included 150 subjects of age group 25-35 years. Out which
75 werenon-smokers pregnant women as a control group and 75 were smoker pregnant women as a study
group. During this stage of pregnancy, the vitamin C levels in the maternal serum were colorimetrically
determined. The respondents also answered a questionnaire about their smoking habits during pregnancy.
Vitamin C intake was measured during the third trimester by monitoring food consumption over a 5-day
period (including Sunday) and vitamin C registration with dietary supplements.
Results: In the present study, we found significant decreased levels of serum vitamin C and in pregnant
cigarette smokers as compared to pregnant non-smokers.Vitamin C was protective for placental abruption in
nonsmokers but not in smokers (P=0.01).
Conclusion: If the production of antioxidants (vitamin C) in smokers is lower compared to pregnant women
who are not smokers, this could aggravate their newborn’s peroxidation problems. Supplementation of
vitamin C tends to be connected with a decrease in placental abruption and preterm birth in pregnant smokers.