A Comparative Study Between Effects Of Ketamine And Fentanyl As Co-induction Agents With Propofol For I-Gel Insertion In Minor Surgical Procedures.

Abstract

Background: The study aimed to compare and determine the success rate, ease of introducing I-gel and
the hemodynamic effects of two adjuvant drugs ketamine and fentanyl, when used with induction agent
propofol in minor surgical procedures.
Methodology: The study comprised of 68 patients of ASA-I & II grading of either gender, aged between 18
to 60 years undergoing minor surgical procedures. Patients were distributed into two groups.
Group K- inj. ketamine 0.5mg/kg & inj. propofol 2mg/kg
Group F- inj. fentanyl 1mcg/kg & inj. propofol 2mg/kg
Results: Both groups K and F were comparable in terms of baseline clinic-sociodemographic variables
such as age, gender, weight, ASA grade and Mallampatti grade. Attempt of insertion was more than one in
26.5% cases of group K and 8.8% cases of group F, showing statistically insignificant difference(p>0.05).
Jaw relaxation was significantly good in group F than group K (p<0.01). Incidence as well as severity
of coughing and limb movement was much higher in group K than group F (p<0.01). Overall excellent
significantly higher condition was observed. Excellent conditions seen in 85.3% and 50% cases belonging
to group F and group K respectively (p<0.01).
Mean total requirement of propofol was 124±24.56 and 110.06±18.95 in cases belonging to groups K and
group F respectively. Thus showing significant difference. Hemodynamic parameters such as heart rate(HR)
and blood pressure(BP) were significantly higher in group K than in group F following induction(p<0.01).
Conclusion: Fentanyl when used as co-induction drug with propofol provides ideal condition for I-gel
insertion, decreases total requirement of propofol & stable hemodynamic response as compared to ketamine
& propofol