Isolation and Selective Drug of Chose for Pseudomonas Aeruginosa as a Causative Agent in Suppurative Otitis Media

Abstract

Background: Chronic Suppurative otitis media (CSOM),is a chronic inflammation of the middle ear and
mastoid cavity, which presents with recurrent (otorrhea) ear discharge through a perforated tympanic
membrane. The bacterial cause for CSOM can include both aerobic and anaerobic bacteria ,the most common
microorganisms found in CSOM are Pseudomonas aeruginosa, Staphylococcus aureus, Proteus mirabilis,
Klebseilla pneumonia , diphtheroid group, Citrobacter sp. and anaerobic bacteria and fungi like Candida sp
as well asAspergillus sp.
P. aeruginosa was the most common iso 30500000) fallowed by S.aurease 27% (27 isolates) , Proteus
mirabilis 11% (11 isolates),E.Coli 11%(11 isolates), Klebseilla pneumonia 9 %(9 isolates), respectively
while other different species was 5% (5 isolates) and 2% (2 isolates) was fungi. Antimicrobial sensitivity
for P. aeruginosa test by VITEK 2 System based on the main inhibitor concentration (MIC).The Piperacillin
showed to be highly sensitive again P. aeruginosa 77.1% (27 isolation ) followed by Meropenem , Imipenem
,Levofloxacin and Amikacin 65.7% (23 isolation), 60%(21 isolation), 40%(14 isolation), 34.2%(12
isolation) respectively while Ciprofloxacin showed to be the les effected again P. aeruginosa 20% (7
isolation). Ceftazidime , Tobramycin and Ciprofloxacin were highly resistance 68.5% (24isolation). 62.8%
(22 isolation) . 54.2%(19 isolation) respectively.