Antibacterial Activity of (+) Usnic Acid against Multi Drug Resistant Acinetobacter baumannii from Clinical Isolates

Abstract

Acinetobacter baumannii (Ab) is developing resistance to a variety of common antibiotics. and become
multidrug resistant, extreme drug resistant, and pan drug resistant pathogens, requiring the identification
of new antibiotics as well as the identification of new plant compounds capable of acting against Ab.
Recent research has revealed MDR Ab co-infections with COVID-19,, raising alarm bells. Since
its isolation, Usnic acid has been investigated for a variety of pharmacological activities, including
antioxidant, antitumor, antibacterial, antifungal, antiviral, antiprotozoal, and insecticidal. Many
Plant-derived drugs show promising activity as new antimicrobial agents against multidrug resistant
(MDR) strains. There is insufficient data to support the antibacterial activity of (+)-UA against MDR
Acinetobacter baumannii..