Effectiveness of Pisang Raja Peel Extract (Musa Paradisiaca L) on Bacterial Growth of Porphyromonas Gingivalis as the Cause of Periodontitis
DOI:
https://doi.org/10.37506/ijfmt.v16i1.17459Abstract
Background. Periodontal disease is a chronic inflammatory infection that causes damage to the
tissue supporting the teeth. The most common periodontal diseases are gingivitis and periodontitis.
Periodontitis is a complex, localized chronic inflammatory disease characterized by the destruction of
connective tissue, periodontal ligaments, and bone supporting teeth. This periodontal disease is caused
by plaque bacteria on the surface of the teeth, where the plaque is a thin layer of biofilm containing
a collection of pathogenic microorganisms such as Porphyromonas gingivalis, Actinobacillus
actinomycetemcomitans, Prevotella intermedia, Tannerella forsythia and Fusobacterium nucleatum
which are soft deposits. Porphyromonas gingivalis is a gram-negative, black pigmented, rod-shaped
anaerobic bacteria. Porphyromonas gingivalis is one of the dominant bacteria in chronic periodontitis
which is found in subgingival plaques. Indonesia is a country with a tropical climate which makes
it rich in biodiversity, which can be used as antibacterial agents. Plantain (Musa Paradisiaca L) is
a fruit that is easy to get, but the skin is rarely used. The Pisang Raja peel (Musa Paradisaca L)
contains chemical compounds saponins, tannins, flavonoids, and alkaloids which have antimicrobial
properties. Objective: To determine the effectiveness of Pisang Raja peel (Musa Paradisiaca L) extract
against the inhibition of Porphyromonas gingivalis bacteria as a cause of periodontitis. Methods: Using
laboratory experimental methods, the test was carried out in the laboratory with the form of research
in the form of Posttest Only Control Design and sampling by random sampling through 4 treatments
and 6 repetitions. Statistical test was One Way Anova. Results: Based on the oneway Anova test, the
concentration group of 16%, 32%, and 64% and the control group obtained a p-value of (p <0.01)
which means that there is a significant difference. Conclusion: Based on the results of this study, it is
shown that the effectiveness of Pisang Raja peel extracts concentrations with concentration 16%, 32%,
and 64% in inhibiting Porphyromonas gingivalis bacteria and control group obtained p-value (p<0,01)
means there was significant correlation. Conclusion: Based on this research that there is effective
correlation Pisang Raja peel extract with concentration 16%, 32%, dan 64% can inhibit the growth
Porphyromonas gingivalis.
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https://creativecommons.org/licenses/by-nc/2.0/deed.en