Comparison of the Effect of Glycemic Control on the Incidence of Fetal Macrosomia and Large for Gestational Age in Gestational Diabetes Mellitus Patients; A Systematic Review

Authors

  • Natasha Tiara Bernadette
  • Budi Prasetyo
  • Sony Wibisono
  • Bambang Purwanto

DOI:

https://doi.org/10.37506/ijfmt.v16i2.17972

Keywords:

diabetic pregnancy, glycemic control, macrosomia, large for gestational age, diabetes control, diabetic therapy

Abstract

Background: Gestational diabetes mellitus (GDM) can be managed with blood glucose control
management, which includes a healthy lifestyle, insulin therapy, and oral anti-diabetic drug (OAD)
medications when needed. Sub-optimally or poorly managed GD Mmay lead to arisk of complications,
one of which is an abnormal growth in the fetus. This study aimed to compare the effect of blood
glucose control management on the incidence of fetal macrosomia and large for gestational age (LGA)
births in patients with GDM. Methods: This systematic review study obtained data from formerly
published studies from the Science Direct database. The article search method used the characteristics
of PICO (Population, Intervention, Comparison, Outcome) and compiled using the Preferred Reporting
Items for Systematic Review and Meta-Analysis (PRISMA) method. Conclusion: The use of medical
nutrition therapy (MNT) and exercise in the therapeutic regimen, as well as routine monitoring of
glycemic levels are very important to control the patient’s glycemic level. The use of metformin can
increase the success of therapy due to reduced levels of LGA and macrosomia in GDM patients

Author Biographies

  • Natasha Tiara Bernadette

    Bachelor Student, Faculty of Medicine,Universitas Airlangga, Surabaya, Indonesia,

  • Budi Prasetyo

    Consultant, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Hospital Surabaya, Indonesia

  • Sony Wibisono

    Senior Lecturer, Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga/Dr. Soetomo General Academic Hospital Surabaya, Indonesia

  • Bambang Purwanto

    Senior Lecturer, Department of Physiology, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia

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Published

2022-04-12

How to Cite

Comparison of the Effect of Glycemic Control on the Incidence of Fetal Macrosomia and Large for Gestational Age in Gestational Diabetes Mellitus Patients; A Systematic Review. (2022). Indian Journal of Forensic Medicine & Toxicology, 16(2), 273-281. https://doi.org/10.37506/ijfmt.v16i2.17972