Stevens-Johnson Syndrome induced by Piroxicam: A Case Report

Authors

  • Cita Rosita Sigit Prakoeswa
  • Emma Hidayati Sasmito
  • Armyta Denissafitri
  • Menul Ayu Umborowati
  • Sylvia Anggraeni
  • Damayanti

DOI:

https://doi.org/10.37506/ijfmt.v16i4.18561

Keywords:

s: Stevens-Johnson syndrome, adverse drug reaction, piroxicam

Abstract

Stevens Johnson Syndrome (SJS) is acute life-threatening mucocutaneous reactions characterized by extensive
necrosis and detachment of the epidermis and mucosal epithelium less than 10% of the total of the total body
surface area. The pathophysiology of SJS is still unclear; however, drugs are identified as the main cause of
SJS in most cases. Drugs are the most important etiologic factor, >20% idiopathic or caused by infection. Many
nonsteroidal anti-inflammatory drugs (NSAID) were suspected. Oxicam derivates showing the highest risk. The
accurate diagnosis, avoidance of the use culprit of the drugs and rapid treatment with symptomatic and supportive
care may improve the prognosis.

Author Biographies

  • Cita Rosita Sigit Prakoeswa

    Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr.
    Soetomo General Hospital, Surabaya, 60286, Indonesia

  • Emma Hidayati Sasmito

    Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr.
    Soetomo General Hospital, Surabaya, 60286, Indonesia

  • Armyta Denissafitri

    Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr.
    Soetomo General Hospital, Surabaya, 60286, Indonesia

  • Menul Ayu Umborowati

    Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr.
    Soetomo General Hospital, Surabaya, 60286, Indonesia

  • Sylvia Anggraeni

    Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr.
    Soetomo General Hospital, Surabaya, 60286, Indonesia

  • Damayanti

    Department of Dermatology and Venereology, Faculty of Medicine, Universitas Airlangga, Dr.
    Soetomo General Hospital, Surabaya, 60286, Indonesia

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Published

2022-10-10

How to Cite

Stevens-Johnson Syndrome induced by Piroxicam: A Case Report. (2022). Indian Journal of Forensic Medicine & Toxicology, 16(4), 154-158. https://doi.org/10.37506/ijfmt.v16i4.18561