Early diagnosis of acute kidney injury by measurement of Interleukin-6 (IL-6) and Hepcidin levels in patients following cardiac catheterization

Authors

  • Hind F. Aref
  • Nazar A. Naji
  • Hadaf D. Ibrahim

DOI:

https://doi.org/10.37506/ijfmt.v16i4.18591

Keywords:

Serum Interleukin-6(IL-6), Hepcidin, AKI, Chronic kidney disease, Cardiac surgery

Abstract

Acute kidney damage is a severe condition common in patients who have undergone heart surgery (catheterization)
and secondary injury is also referred to as being synonymous with surgery. The goal of this research is to determine
the rate of serum urea, Interleukin-6 (IL-6) and Hepcidin levels in patients with acute renal injury (AKI) following
cardiac catheterization. The study included 81 patients (64 males and 17 females) ranging in age from 40 to 75
years. Data from most patients is reported in the form of an age, gender and smoking background questionnaire.
The results indicate a significant increase in serum urea, Interleukin-6 (IL-6) and Hepcidin levels in patients with
severe renal insufficiency after cardiac catheterization in (79%) males versus (21%) females. According to the
outcomes of this study, improved risk prediction could improve patient monitoring and treatment after surgery,
as well as direct patient treatment and decision making. Also, the findings show that they enhance participation
in AKI interventional trials.

Author Biographies

  • Hind F. Aref

    Researcher, Department of Chemistry, College of Science, University of Baghdad, Baghdad 10013,
    Iraq, 

  • Nazar A. Naji

    Professor Department of Chemistry, College of Science, University of Tikrit, Salah Al Deen
    34001, Iraq

  • Hadaf D. Ibrahim

    Professor Department of Clinical Biochemistry, College of Medicine, University of
    Baghdad, Baghdad 10013, Iraq.

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Published

2022-10-10

How to Cite

Early diagnosis of acute kidney injury by measurement of Interleukin-6 (IL-6) and Hepcidin levels in patients following cardiac catheterization. (2022). Indian Journal of Forensic Medicine & Toxicology, 16(4), 248-253. https://doi.org/10.37506/ijfmt.v16i4.18591