Comparative Antimicrobial and Wound Healing Potentiality of Onion, Garlic and Ginger

Authors

  • Km Renu Singh
  • Sanjita Das
  • Shivani Shrivastava
  • Shruti Dhasman
  • Irfan Khan

DOI:

https://doi.org/10.37506/ijfmt.v16i4.18602

Keywords:

: wound healing, antimicrobial, onion, garlic, ginge

Abstract

Objective: The aim of the research is to investigate the antimicrobial and wound healing activities of onion (Allium
cepa) bulbs, garlic (Allium sativum) cloves, and ginger (Zingiber officinale) rhizomes.
Method: After extraction of onion, garlic and ginger with ethanol, their antimicrobial activity was observed
following disc diffusion method. The creams of the nanoemulsion of the dried extracts were prepared and
subjected to evaluate their wound healing potentiality against both the excision and incision models.
Result: The present study showed the significant (*p<0.001) wound healing activity of the onion, garlic, ginger and
combination of onion garlic and ginger creams in the excision and incision wound model. In excision (*p<0.001)
and incision (*p<0.001) model ginger showed maximum potential. The antibacterial efficacy of onion bulb, garlic
clove, and ginger rhizome extracts was tested against gram-negative and gram-positive bacterial strains. The
highest inhibitory zone against Escherichia coli appeared to be ginger (17 mm).
Conclusion: The extracts of onion, garlic, and ginger have antibacterial action against bacterial pathogens and can
be used to treat microbial infections. According to the findings of this study, all the extracts had a positive effect on
the excision and incision models, where ginger was observed to be the most effective among them.

Author Biographies

  • Km Renu Singh

    Research Scholar, Noida Institute of Engineering and Technology
    (Pharmacy Institute), Plot No.19, Knowledge Park-II, Greater Noida, Uttar Pradesh, India

  • Sanjita Das

    HOD and Professor, Noida Institute of Engineering and Technology
    (Pharmacy Institute), Plot No.19, Knowledge Park-II, Greater Noida, Uttar Pradesh, India

  • Shivani Shrivastava

    Research Scholar, Noida Institute of Engineering and Technology
    (Pharmacy Institute), Plot No.19, Knowledge Park-II, Greater Noida, Uttar Pradesh, India.

  • Shruti Dhasman

    Research Scholar, Noida Institute of Engineering and Technology
    (Pharmacy Institute), Plot No.19, Knowledge Park-II, Greater Noida, Uttar Pradesh, India.

  • Irfan Khan

    Research Scholar, Noida Institute of Engineering and Technology
    (Pharmacy Institute), Plot No.19, Knowledge Park-II, Greater Noida, Uttar Pradesh, India

Downloads

Published

2022-10-10

How to Cite

Comparative Antimicrobial and Wound Healing Potentiality of Onion, Garlic and Ginger. (2022). Indian Journal of Forensic Medicine & Toxicology, 16(4), 289-298. https://doi.org/10.37506/ijfmt.v16i4.18602