Comparative Antimicrobial and Wound Healing Potentiality of Onion, Garlic and Ginger
DOI:
https://doi.org/10.37506/ijfmt.v16i4.18602Keywords:
: wound healing, antimicrobial, onion, garlic, gingeAbstract
Objective: The aim of the research is to investigate the antimicrobial and wound healing activities of onion (Allium
cepa) bulbs, garlic (Allium sativum) cloves, and ginger (Zingiber officinale) rhizomes.
Method: After extraction of onion, garlic and ginger with ethanol, their antimicrobial activity was observed
following disc diffusion method. The creams of the nanoemulsion of the dried extracts were prepared and
subjected to evaluate their wound healing potentiality against both the excision and incision models.
Result: The present study showed the significant (*p<0.001) wound healing activity of the onion, garlic, ginger and
combination of onion garlic and ginger creams in the excision and incision wound model. In excision (*p<0.001)
and incision (*p<0.001) model ginger showed maximum potential. The antibacterial efficacy of onion bulb, garlic
clove, and ginger rhizome extracts was tested against gram-negative and gram-positive bacterial strains. The
highest inhibitory zone against Escherichia coli appeared to be ginger (17 mm).
Conclusion: The extracts of onion, garlic, and ginger have antibacterial action against bacterial pathogens and can
be used to treat microbial infections. According to the findings of this study, all the extracts had a positive effect on
the excision and incision models, where ginger was observed to be the most effective among them.
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