Coffea Canephora Extract as Antibacterial Agent against Escherichia coli
DOI:
https://doi.org/10.37506/ijfmt.v16i4.18660Keywords:
Coffea canephora, Coffea canephora extract, Antibacterial, Antibacterial agent, Escherichia coli, Gram PositiveAbstract
Introduction: This research is investigate antibacterial activity of Coffea canephora extract against Gram-Positive
Escherichia coli.
Methods: An experimental laboratory with post-test only group design, investigating antibacterial activity of
Coffea canephora extract in concentrations 4%, 16%, 25%, 33%, 39% and 44% were observed and measured mean
diameter inhibitory zone then analysed by statistical and sensitivity test. Sensitivity criteria according standard of
Clinical and Laboratory Standarts Institiute (CLSI). Statistical test using Kruskal-Wallis and Mann-Whitney Test.
Conclusion: In The Coffea canephora extract showed lowest concentration to inhibit Escherichia coli was 33%
(Mean : 9mm) although categorized as resistant. Greatest concentration 44% (Mean: 13.75mm) was categorized
as intermediate. Statistical analysis using Kruskal-Wallis showed significant difference in all concentration and
Mann-Whitney showed significant mean diameter inhibitory zone in concentration 33%, 39% and 44%. In this
study we showed Coffea canephora extract perform antibacterial activity against Escherichia coli although in current
study no sensitive concentration found. Increase concentration correlated with increase mean diameter inhibitory
zone which indicated antibacterial activity.
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