Proteomic Approaches vis-a-vis Forensic Evidence Analysis: Forensic Proteomics a Valuable Tool

Authors

  • Ajay Kumar Gautam
  • Vijay Yadav
  • Anurag Sharma
  • Sameer S. Bhagyawant
  • Sanjeev K Gupta
  • Deepa Verma

DOI:

https://doi.org/10.37506/ijfmt.v17i1.18899

Keywords:

Proteomics, Forensic, serology, body fluid, evidence.

Abstract

Proteomics is a valuable tool for identifying biological systems because it allows researchers to study all the
proteins in an organism or system on a large scale. Advanced proteomic techniques can be used in the forensic
field as a confirmatory and complementary approach to well-designed genomic analysis. When nucleic acids
are missing or destroyed at the crime scene, it is particularly beneficial for efficient and reproducible peptide
and protein analysis, identification, and characterization in a variety of biological and non-biological contexts. In
forensic sciences, this could help identify new biomarkers. Unlike DNA markers, protein markers prevent sample
contamination while giving quantifiable and highly reliable data that can be evaluated employing databases.
They are used in forensics to identify body fluids, ethnic groups, genders, and individuals, and to estimate postmortem intervals from decomposition fluid, bone and muscle samples. Our current review focuses on a wide
spectrum of human samples used in forensic proteomics, as well as recent research achievements. This review is
for forensic investigators who want to learn and explore more about proteomics and how to get more information
from biological evidence.

Author Biographies

  • Ajay Kumar Gautam

    Senior Scientific Officer, Crime Scene Management Division, Forensic Science
    Laboratory, Govt. of NCT of Delhi, India, 110085

  • Vijay Yadav

    Assistant Professor, Institute of Forensic Science & Criminology, Bundelkhand University, Jhansi, India.

  • Anurag Sharma

    Assistant Director, Crime Scene Management Division, Forensic Science Laboratory, Govt. of NCT of Delhi, India, 110085

  • Sameer S. Bhagyawant

    Associate Professor, School of Studies in Biotechnology, Jiwaji University, Gwalior, India, 474011.

  • Sanjeev K Gupta

    Assistant Director, Crime Scene Management Division, Forensic Science Laboratory, Govt. of NCT of Delhi, India, 110085

  • Deepa Verma

    Director, Forensic Science Laboratory, Govt. of NCT of Delhi, India, 110085

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Published

2022-12-21

How to Cite

Proteomic Approaches vis-a-vis Forensic Evidence Analysis: Forensic Proteomics a Valuable Tool. (2022). Indian Journal of Forensic Medicine & Toxicology, 17(1), 82-87. https://doi.org/10.37506/ijfmt.v17i1.18899