Prognostic Biochemical Markers Predicting Severity Caused by COVID 19: A Retrospective Observational Study Conducted in a Small Health-care Set UP in Western U.P.

Abstract

Background: For assessment of mild to severe outcome points of SARS COV-2 we need to observe patients with
comorbidities along with basic laboratory markers like NLR, PLR, CRP, D-dimer, serum Ferritin etc. For the
prediction of SARS COV-2 severity our study aims at basic available laboratory prognostic biomarkers.
Methods and Result: Our study included 46 patients with mild, moderate and severe outcomes which were
categorised according to CRP, Serum Ferritin and D- dimer with p-Value < 0.001 for both outcomes which are
significant as compared to outcome patients with p-Value = 0.01 which is slightly less significant.
Conclusion: A raised value of CRP, ferritin, D-dimer and involvement of male gender and old age patients were
associated with severity of the disease.
Among these parameters, D-dimer was known to be the best predictor of the outcome.