Exploring the Hormonal Profiles of Beedi-Rolling Women and Unravelling Health Implications

Authors

  • Pardhanandana Reddy Penagaluru Bhagwan Mahavir Medical Research Centre and MAA Research Foundation
  • Baluka Vanitha Bhagwan Mahavir Medical Research Centre
  • Busarapu Manideep Bhagwan Mahavir Medical Research Centre
  • Shehnaz Sultana Bhagwan Mahavir Medical Research Centre
  • Madhuri Lakkampelly Bhagwan Mahavir Medical Research Centre
  • Prashanth Chiliveri Bhagwan Mahavir Medical Research Centre

DOI:

https://doi.org/10.37506/75e4nm22

Keywords:

Beedi rolling, Estrogen, Progesteron, Follicle stimulating hormone (FSH), Testesterone

Abstract

Background: In the rural regions of Telangana State, many women are actively involved in the occupation of beedi rolling. Cigarette smoke either active or passive exerts deleterious effects on reproductive organs and function by means of both direct toxic influences, termed ovotoxicity, and the reduction of hormone secretion.

Methods: The study involved a cohort of 320 women employed as beedi rollers and 280 women with no occupational exposure to chemicals for comparison. Serum samples were used to estimate the levels of Estrogen, Progesterone, Testosterone, Follicle Stimulating Hormone, luteinizing hormone, T3, T4 and TSH using Sandwich and competitive ELISA methods.

Conclusion:  The findings of the current study unveiled compelling statistical significance in the levels of estrogen, progesterone, luteinizing hormone (LH), follicle-stimulating hormone (FSH), T3 and T4. In conclusion, our study reveals a noteworthy correlation between beedi rolling and alterations in hormonal profiles of rural women in Telangana.

References

Ruan X, Mueck AO, Impact of smoking on estrogenic efficacy. Climacteric.2015;18:38–46.

Lilach Marom-Haham and Adrian Shulman, Cigarette smoking and hormones. Curr Opin Obstet Gynecol.2016; 28.

Michnovicz JJ, Hershcopf RJ, Naganuma H, et al., Increased 2-hydroxylation of estradiol as a possible mechanism for the antiestrogenic effect on cigarette smoking. N Engl J Med.1986; 315:1305–1309.

Quatrtrochi LC, Vu T, Tukey RH, The human CYP1A1 gene and induction by 3-methylchlorantrene: a region of DNA that supports AH receptor binding and promotor specific binding. J Biol Chem. 1994; 269:6949–6954.

Hankinson O, The Aryl hydrocarbon receptor complex. Annu Rev Pharmacol Toxicol.1995;5:307–340.

Meek MD, Finch GL, Diluted mainstream cigarette smoke condensates activate estrogen receptor and aryl hydrocarbon receptor mediated gene transcription. Environ Research.1999;80:9–17.

John A. Baron, Carlo La Vecchia, Fabio Levi,The antiestrogenic effect of cigarette smoking in women. American Journal of Obstetrics and Gynecology.1990;162(2):502-514.

Baluka V, Prashanth C, Reddy P.P, Assesment on Reproductive Performance and Hormonal Studies in Rural Women Beedi Rollers in Jagitial District of Telangana. Canadian Journal Biotechnology.2017;1:165.

Downloads

Published

2024-09-20

Issue

Vol. 15 No. 4 (2024): Indian Journal of Public Health and Research Development

Section

Original Article

License

Copyright (c) 2024 Pardhanandana Reddy Penagaluru, Baluka Vanitha, Busarapu Manideep, Shehnaz Sultana, Madhuri Lakkampelly, Prashanth Chiliveri

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

https://creativecommons.org/licenses/by-nc/2.0/deed.en

How to Cite

Exploring the Hormonal Profiles of Beedi-Rolling Women and Unravelling Health Implications. (2024). Indian Journal of Public Health Research & Development, 15(4), 297-301. https://doi.org/10.37506/75e4nm22