Effect of Family focused therapy among caregivers and patients on prognosis of bipolar disorder patients: A systematic Review and Meta Analysis
DOI:
https://doi.org/10.37506/jt4de287Keywords:
Family focused therapy, Bipolar Disorder, Depression, Mania, Hypo- mania.Abstract
Abstract: Background: Bipolar affective disorder is a chronic condition with high relapse rate, morbidity, and psychosocial impairment that often persist despite pharmacotherapy highlighting the need for psychosocial treatments. Non pharmacological intervention like family focused therapy (FFT) can improve the disease outcome i.e. depression and mania symptoms and reduces relapse rate.
Objective: To assess the effect of family Focused therapy on disease outcome of bipolar affective disorder patients.
Materials and Method:
In this review Pub med, Medline, Google scholar, Cochrane database between 1999 to 2024 were searched by using RCT, reviews fulfilling inclusion criteria were included. Randomized controlled trials comparing family focused therapy with pharmacotherapy as usual, enhanced care, added in the study. Adolescents without any psychotic feature, any neurological disorders, and substance use disorders were included in this review. Two independent reviewers extracted data and assessed the quality of the trials. The results were presented in form of forest Plots.
Results: A total of 13 studies, including 1208 bipolar patients, were included in the review for qualitative analysis. Amongst them eight studies involving.584 bipolar patients receiving Family focused therapy included in meta analysis in depression and mania outcome .Overall, there was a reduction in depressive and manic symptoms among the bipolar patients receiving family focused therapy compared to treatment as usual and enhanced care. For depression{SMD:-0.38(-0.67,-0.08,95%CI)}.For Mania SMD:-0.45(-0.77,-0.12,95%CI)}.Significant reduction of relapse rate were found .No significant changes of medication adherence and quality of life were found.
Conclusion: Family focused therapy adjunct to pharmacotherapy in bipolar affective disorder is effective in reducing depressive and manic symptoms. Reducing number of mood episodes, and hospitalization and increased time between episodes.
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